ea0048oc3 | Oral Communications | SFEEU2017
Behary Preeshila
, Tharakan George
, Al-Najim Werd
, Brown Adrian
, Miras Alexander
, Stoenchev Kostadin
, Chahal Harvinder
, Purkayastha Sanjay
, Moorthy Krishna
, Ahmed Ahmed
, Bloom Steve
, Tan Tricia
Introduction: Improvement in glycaemia is observed early after Roux-en-Y Gastric Bypass surgery (RYGB) in patients with diabetes. Commonly cited mechanisms to account for these changes include the elevation of gut hormones, increase in bile acids levels, changes in the gut microbiota and calorie restriction. Calorie restriction is believed to play a role in improving hepatic insulin sensitivity and reduce hepatic glucose output early after RYGB, in the context of non-significa...